Syllabus | Nutritional Biochemistry | B. Sc. (Nutrition & Dietetics) | First Year

Topic

Domain

Hours

Module 1

• Unit of measuring energy

• calorific value of food

• BMR & factors affecting it

•  SDA of food

• calculation of energy requirement,

•  balanced diet

• Nutrition in health & diseases (protein energy malnutrition)

• Definition of energy
• Unit of energy i.e. calories and joules
• Energy Balance i.e. positive & negative energy balance
• Basal Metabolic Rate:-
  • • • Factors considered while measuring BMR
      • Factors affecting BMR
• Calculation of energy
• Definition of Balance diet

Desirable to know

• Food sources that provide energy
• Nutrition in health & diseases

Nice to know

• Energy value of different nutrients
• Factors considered in planning balance diet

4

Module 2

• Introduction

• Definition

• Classification

• Biomedical importance

• Brief outline of metabolism: Glycogenesis

• Glycogenolysis

• Glycolysis,

• Citric acid cycle & its significance,

• HMP shunt

• Gluconeogenesis

• regulation of blood glucose level

• Definition of carbohydrate
• Classification of carbohydrate
• Definition of glycolysis
• Reactions of glycolysis
• Definition of citric acid cycle
• Reactions of citric acid cycle
• Pathway of gluconeogenesis
• Pathway of glycogenolysis
• Location of HMP Shunt pathway
• Reaction of HMP Shunt pathway
• Metaboli and hormonal mechanism of glucose homeostasis

Desirable to know

• biomedical importance of carbohydrate
• digestion & absorption of carbohydrate
• key reactions of gluconeogenesis
• regulation of glycogen metabolism
• stages of maintenance of blood glucose level

Nice to know

• Properties of monosaccharide
• Metabolism of glucose
• Glucose transport and insulin secretion
• Sites of gluconeogenesis
• Glycogen storage disease

7

Module 3

• Definition

• classification

• Essential & non essential amino acids

• Definition of amino acids
• Classification of amino-acids
• Difference between essential & non essential amino acids

Desirable to know

• Properties of amino acids
• Peptide Bonds

Nice to know

• Biomedical importance

1

Module 4

• Introduction,
• definition,
• classification,
• biomedical importance Metabolism:
  • Transformation
  • Decarboxylation
  • Ammonia formation & transport
• Urea cycle

• Definition of protein
• Classification of proteins

• Urea cycle
• Digestion, absorption process

Desirable to know

• Structure of protein
• Functions of protein

Nice to know

• Biomedical importance
• Denaturation of proteins

6

Module 5

• Introduction
• Definition
• Classification
• Biomedical importance
• Essential fatty acids
• Identification of fats &oils (saponification no, acid no, iodine no, acetyl no, reichert- miesel no. etc.)
• Brief outline of metabolism
• Beta oxidation of fatty acids
• ketosis

• The chemical structure of lipids
• The Classifications of fats
• Oxidation of fatty acids
• ketosis

Desirable to know

• Methods of identification of fats
• Beta oxidation pathway
• Biochemical abnormalities in diabetic ketoacidosis

Nice to know

• Biomedical importance
• Properties of fatty acids
• Principle of management

8

Module 6

• Introduction
• definition
•  classification
•  coenzymes
• isoenzymes
•  properties
•  factors affecting enzyme action
•  enzyme inhibition
•  diagnostic value of serum enzymes
  • Creatinine kinase
  • Alkaline phosphatase
  • Acid phosphatase
  • LDH,
  • SGOT,
  • SGPT,
  • Amylase,
  •  Lipase,
• Carbonic anhydrase

• Definition of enzymes
• Classification of enzymes
• General properties of enzymes
• IUBMB system of nomenclature
• Isoenzymes
• Diagnostic value of serum enzymes

Desirable to know

• Chemical nature of enzymes
• Factors affecting the rate of enzyme catalyzed reaction
• Properties of isoenzymes

Nice to know

• Biomedical importance
• Measurement of enzyme activities
• Physiological importance of isoenzymes

6

Module 7

• pH
• Buffers
• Acidosis
• Alkalosis

• Importance of water in human body
• Components of body fluid
• Various functions of water

Desirable to know

• sources
• The health effects due to water imbalance

Nice to know

• The normal requirement of water in human body

2

Module 8

• Classification,
• general mode of action,
• hormones of
  • Pituitary,
  • Thyroid,
  • Parathyroid,
  • Adrenals,
  • Reproductive Glands,
  • Pancreas,
• hormonal disorders,
• Counter regulatory hormones.

• Introduction of hormones
• Classification of hormones
• Functions of different hormones
• Hormonal disorders

Desirable to know

• Chemical nature of hormones
• Active form of hormone

Nice to know

• Hormone receptors
• Regulation of hormone secretion

6

Module 9

• Water & fat soluble vitamins,
• sources,
• requirement,
• deficiency disorders
• Biochemical functions.

• Introduction of vitamins
• Classification of vitamins i.e. fats soluble & water soluble vitamins
• Introduction of fat soluble vitamins
• Introduction of water soluble vitamins

Desirable to know

• Food sources
• Biochemical functions
• Deficiency disorder

10

Module 10

• Distribution of fluids in the body
• ECF
• ICF
• Water metabolism
• dehydration

• distribution & composition of fluid in human body
• water metabolism
• fluid balance
• disorder of water metabolism

Desirable to know

• Functions of water
• Distribution of total body water
• Regulation of water balance

Nice to know

• Biomedical importance

3

Module 11

• Definition
• Types
• Features
• Gestation diabetes mellitus
• Glucose tolerance test
• Glycosurias
• Hypoglycemia & its causes

• Introduction to disease
• Types of diabetes mellitus
• Nutritional management

Desirable to know

• Diagnostic test
• Food sources that provide energy

3

Module 12

• Protein metabolism
• Lipid Metabolism
• Measurements of serum enzyme levels

Bile pigment metabolism: Jaundice – its types and their biochemical findings.

• Introduction to liver function test
• Liver function test
• LFT profile

Desirable to know

• Indications of LFT
• Indications of ranges

15

Module 13

• Indications of renal function test
• renal function test

Desirable to know

• Tubular function test
• Evaluation of filtration barrier

Nice to know             

• Functions of kidney

4

Module 14

• Introduction to tumor markers
• Types of tumor markers
• Clinical applications of tumor marker

3

Module 15

• Introduction to immunity
• Introduction to immune system
• Hypersensitivity
• Functions of immunoglobulins

Desirable to know

• antibodies

2