BND 1st Year
Nutritional Biochemistry
Theory – 80 hrs.
Practical: – 40 hours
| S. No |
Contents |
Learning objectives |
Teaching Guidelines |
Methodology |
Time |
| 1 | Basics of energy metabolism, nutrition & dietetics – | Define the term energy Describe the unit of energy Enumerate the term BMR and explain the factors affecting BMR Understand and explain the methods applied to calculate the energy requirement of different categories |
To cover the topic-
|
Student seminar |
4 |
| 2 | Chemistry of carbohydrates & their related metabolism –. | Identify and explain the major monosaccharide’s, disaccharides, and polysaccharides found in the human body and diet Describe the overall purpose of glycolysis, its reactants and products, its cellular localization, and its tissue distribution Describe the overall purpose of gluconeogenesis, its reactants and products, its cellular localization, and its tissue distribution |
To cover the topic-
|
Didactic method with Power point presentation |
7 |
| 3 | Amino acids – | Describe amino acid structure and properties. Understand and write the classification of amino acids Define peptide bond formation in amino acid. |
To cover the topic-
|
Video presentation/ Didactic |
1 |
| 4 | Chemistry of Proteins & their related metabolism –. | Identify and explain the major classification of protein Describe how the body digests proteins Define various aspects of protein metabolism, its transport, and cellular metabolism, regulation at substrate, enzyme, hormonal & organ level and associated disorders. Explain how the urea cycle prevents toxic concentrations of nitrogen |
To cover the topic-
|
Didactic method with |
6 |
| 5 | Chemistry of Lipids & their related metabolism – | Differentiate between the different types and classifications of fatty acid obtained from our diet Describe the process digestion and absorption of fatty acid and triglycerides, as well as the medical ramification of lipid malabsorption Distinguish between the four major lipoprotein complexes (chylomicrons, VLDL, LDL and HDL) Describe approaches to Therapeutic Lifestyle Changes (TLC) that can aid in reducing the risk of CHD |
To cover the topic–
|
Didactic method followed by student interaction session |
8 |
| 6 | Enzymes | Describe how enzymes function as biological catalysts and name & classify them Describe the 4 characteristics of enzymes Describe the effect of temperature, pH, concentration of enzyme and concentration of substrate on enzyme activities Understand and explain reversible and irreversible inhibition Understand and learn different diagnostic values of serum enzymes |
To cover the topic-
|
Teachers seminar, Tutorials |
6 |
| 7 | Acid base balance concepts & disorders – | Indicate whether the pH level indicates acidosis or alkalosis List major sources of acids in the body Identify the major chemical buffer systems in the body Identify the cause of the pH imbalance as either respiratory or metabolic Distinguish between acidosis and alkalosis resulting from respiratory and metabolic factors |
To cover the topic-
|
Student seminar by |
2 |
| 8 | Hormones | Understand and describe the classification of hormones
|
To cover the topic-
|
Power point presentations/ Student Seminars/
|
6 |
| 9 | Vitamins – | understand the nutrient requirements, recommended dietary allowances and biochemical functions of vitamins in humans To acquire a fundamental background of the deficiency disorders related to the deficiency of water soluble and fat soluble vitamins |
To cover the topic-
|
Student seminars followed by group discussion and short type questions |
10 |
| 10 | Water metabolism-. | learn the distribution of water and electrolytes in the body and their exchanges learn the mechanism of normal water and electrolyte balance in health Study the regulatory mechanisms by which the water and electrolytes balance is maintained Understand and explain the abnormalities of water and electrolyte metabolism |
|
3 |
|
| 11 | Hyperglycemia & hypoglycemia | Understand and explain the term diabetes mellitus, its type, clinical symptoms and their methods of determination. Enumerate the term associated with diabetes mellitus and health effects of hypoglycemia. |
Diabetes mellitus –
|
Didactic lecture by using slides and discuss case studies with examples |
3 |
| 12 | Liver functions and their assessment – | To learn and understand various functions of liver Learn the classification of various liver function test based on different functions of the liver Classify jaundice, its type and learn the liver function test associated with it |
Based on – Carbohydrate metabolism
|
Didactic method |
15 |
| 13 | Renal functions tests – | To understand and explain the physiological aspects of kidney. Classify the various function test based on Glomerular Filtration Rate (GFR) |
Various tests, GFR & clearance. | Teachers seminar followed by exercise |
4 |
| 14 | Tumor markers & their clinical applications | understand the ideal characteristics of a tumor marker Understand and enumerate the role of tumor markers for diagnosis and management of patients with cancer. Understand the role of tumor markers for therapeutic selection |
Including oncofeatal antigens, CEA etc. |
Didactic method by power point presentation |
3 |
| 15 | General concepts & functions of immunoglobulins | Define immunoglobulins Classify immunoglobulins, WHO classification Learn and explain the important properties of each class of immunoglobulins Study and enumerate the functions of each class of immunoglobulins |
Didactic method by power point presentation |
2 |
PRACTICALS
1. Identification of carbohydrates (Qualitative Tests)
2. Identification of proteins (Qualitative Tests)
3. To study general properties of the enzyme Urease & Achromatic time of salivary amylase.
4. Estimation of glucose in urine by Benedict’s methods
5. Urine analysis – normal & abnormal constituents of urine.
6. Blood glucose estimation.